He is best known for his prominent roles in various hit TV series. Roles such as his character Cederic Daniels in The Wire, Phillip Broyels in Fringe, and Mathew Abbadon in Lost. Aside from television Lance also does theater and film work, recently appearing in the 2013 thriller White House Down.
Reddick was born in Baltimore, Maryland. He attended Friends School of Baltimore, graduating in 1980. As a teenager, he studied music at the Peabody Preparatory Institute and a summer program teaching music theory and composition at The Walden School.After attending the Eastman School of Music at the University of Rochester, he moved to Boston, Massachusetts in the 1980s and enrolled in the Yale School of Drama in 1991.
Reddick was cast as Cedric Daniels in the HBO series The Wire, after having also auditioned for the roles of Bubbles and Bunk Moreland. He joined ABC's hit series Lost in 2008, where he played Matthew Abaddon, an employee of Charles Widmore, in multiple episodes. He was the third of five actors from the HBO hit series Oz to star in the drama. Producers Damon Lindelof and Carlton Cuse have said they were interested in Reddick for the part of Mr. Eko but he was unavailable due to filming The Wire so they approached Akinnuoye-Agbaje instead.
Reddick released his debut album Contemplations & Remembrances in 2007 and in early 2008 he was cast in a key role for the pilot of Fringe in which fellow Oz actor Kirk Acevedo also had a regular role. Reddick played Phillip Broyles, the head of an FBI department investigating paranormal activities. Reddick described the hard-driving character as "a real hard-ass, but he's also one of the good guys." Like Lost, Fringe is co-created and produced by J. J. Abrams.
There was some doubt about whether Reddick could appear in both Lost and Fringe in the 2008–2009 television season. However, Abrams stated that while being a series regular on Fringe, he would do episodes of Lost whenever required. He appeared in the 2013 thriller White House Down. He stars in the YouTube web series DR0NE, of which he is a co-producer.
He recently voiced the character Commander Zavala in the 2014 video game Destiny.
Reddick currently resides with his wife Stephanie in Los Angeles, California. He is a promoter for Cree Light Bulbs.