- Edward Mordrake is born with a second face on the back of his head.
- Edward becomes a patient of Bedlam Hospital.
- Edward murders a nurse and breaks out of the hospital.
- Edward commits suicide by hanging.
Late 1920s/ Early 1930s
- Elsa Mars loses her legs in a failed snuff film.
- Massimo Dolcefino crafts Elsa's prostheses.
- Elsa leaves Germany and travels to America with gypsies.
- Shortly afterward, Elsa adopts Pepper and begins collecting her freaks.
- Stanley takes in Maggie, who had been pick-pocketing on the streets.
- Twisty the Clown leaves Rusty Westchester's Traveling Carnival and returns home to Jupiter, Florida.
- Twisty the Clown maims himself while attempting suicide via shotgun.
- Chester Creb murders his wife Lucy and her girlfriend Alice, for mocking his relationship with his dummy, Marjorie.
- Dell kills a man in Chicago and flees with Desiree.
- Bette Tattler kills her mother Eudora.
- Bette and Dot become members of Fraulein Elsa's Cabinet of Curiosities.
- Twisty the Clown murders Troy and kidnaps Bonnie Lipton.
- Twisty the clown kidnaps Corey Bachman and kills his parents.
- Jimmy Darling kills Detective Bunch to protect the twins.
- Meep is framed by Dell for the detective's death and is arrested.
- Meep is killed in prison.
- Twisty the Clown kills the owner and an employee of a toy store.
- Dell and Desiree become members of Fraulein Elsa's Cabinet of Curiosities.
- Dandy makes an attempt to become a member of Fraulein Elsa's Cabinet of Curiosities but is turned down.
- Dandy becomes the protégé of Twisty.
- Meep is framed for Jimmy's crime and goes to jail where he is murdered.
- Ethel discovers she has cirrhosis.
- Maggie becomes a member of Fraulein Elsa's Cabinet of Curiosities.
- Twisty the Clown kidnaps Mike.
- Elsa summons Edward Mordrake.
- Edward Mordrake visits Ethel, Suzi, Paul, Pepper, Salty and Elsa.
- Dandy kidnaps Jimmy and Maggie for Twisty.
- Edward Mordrake kills Twisty and adds him to his "group of freaks."
- Bonnie, Corey, Mike, Jimmy and Maggie escape from Twisty's clutches.
- Dandy kills Dora and Gloria has her buried in the yard.
- Desiree discovers that she isn't hermaphrodite.
- Dandy kills Andy.
- Dell kills Ma Petite so that Stanley can sell her body to a museum.
- Elsa Mars kills Ethel Darling.
- Dandy kills his mother Gloria.
- Dandy commits the Tupperware Party Massacre killing 8 people, and has Jimmy framed for it.
- Jimmy has his hands cut off and sold to a museum so he can afford a lawyer.
- Regina Ross finds out that Dandy murdered Dora and brings in a detective, but Dandy bribes the detective to kill her and cover up Dandy's crimes.
- Salty dies of a stroke.
- Stanley decapitates Salty's corpse (after Salty's funeral), and sells his head to a museum.
- Pepper is framed for her nephew's murder and sent to Briarcliff Manor.
- Pepper befriends Sister Mary Eunice (establishing the connection between Freak Show and Asylum).
- Maggie Esmerelda brings Desiree to the museum where she is shown the preserved body of Ma Petite along with Salty's head.
- Elsa Mars shoots Dell Toledo after he confesses to killing Ma Petite.
- The Freaks find out what Stanley has been doing and cut his arms off and lock him in a cage as revenge.
- Chester tries to rehearse a magic trick which goes wrong, and in a fit of rage, he kills Maggie by sawing her in half.
- Elsa sells the Freak Show to Dandy.
- Paul stands up to Dandy for mistreating the freaks and announces he's quitting, throwing Dandy into rage.
- Dandy massacres most of the freaks, in this order: Paul, Penny, Toulouse, Suzi, Ima Wiggles , and Amazon Eve.
- The Tattler twins trick Dandy into thinking they're going to marry them.
- Jimmy, Desiree, and Bette and Dot Tattler kill Dandy to avenge his victims' deaths.
- Elsa becomes famous by her show in Hollywood.
- Edward Mordrake murders Elsa on her Halloween show, but he doesn't add her to his group.
- Elsa makes it to the afterlife, where she is greeted by Ma Petite and Ethel Darling.
- Jimmy Darling marries the twins
- The twins become pregnant